About :
We develop Microfluidic chip and biosensors based point-of-care technologies for Biomedical and other applications
Our group primarily work under four verticals:
1) Microfabricated chips with microfluidic setup for complex analysis – e.g. on-chip PCR; on-chip CTC detection; capillary electrophoresis microchips for separation and analysis of chemicals in a mixture, e.g. neurochemicals, pesticides etc.; impedimetric estimation of proteinic biomarkers on chip; droplet microfluidics. These work also involve hardware development wherein our group have expertise in taking these technologies to TRL6+.
2) Paper fluidics – involving low-cost solutions, including LFA technology in a multiplexed setup.
3) Handheld devices, e.g. glucometer with saliva as test medium, in which we have undertaken complete hardware integration with optical components, etc.
4) Assay development, including SELEX based novel aptamer generation.
While our strength lies on both fronts: hardware and assay development, we seek to expand our work on novel biomarkers, which would have definitive future towards commercialization. Besides, we seek to work on nanomaterials which can have selective DNA binding and reporting abilities, e.g. in CRISPR-CAS9 and fluorophore-quencher pair.
News and accomplishments from lab
Intel Corp. and DST India supported project under Indo-US (IUSSTF) umbrella where 30 scientists along with their team were involved from India and USA was acknowledged by IUSSTF. Click here for video.
2021: Dr. Sandeep Jha receives DST SERB-STAR Award for outstanding performance of Principal Investigators (PIs) of SERB Projects
Dogra Educational Endowment Award by IIT Delhi to student Tanu Bhardwaj for best scientific publication in Indian Institute of Technology, Delhi (2019- 2020).
Best scholar award in Biomedical Engineering to Tanu Bhardwaj by International Multidisciplinary Research Foundation (2020).
Appan Roychoudhury Received Distinction in Ph.D. thesis for 2019 submission by IIT Delhi
Areas of Interest:
Fabrication of biosensors (optical, piezoelectric, capacitive, electrochemical); nanoparticle sensing; microfabricated microfluidic lab-on-a-chip for PCR and flow-cytometry applications; capillary electrophoresis microchip; immobilization and stabilization of biomolecules in synthetic and natural polymers, etc.